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A reduction in dose or change to another NSAID may decrease the side effects so that you can continue to take the treatment. Alternatively, your doctor may recommend a different pain relieving medicine with fewer potential side effects, such as paracetamol.

There are also a number of other uncommon side effects. Read the leaflet that comes with the medicine, which lists all the precautions and possible side effects. However there is a small but significant increased risk of CV adverse effects such as heart attack, angina or stroke with both selective and nonselective NSAIDs.

The risk is higher in those with other CV risk factors such as a previous CV event e. Due to these potential adverse effects, any NSAID should be used in the minimum effective dose and for the shortest possible time. If you have any questions or concerns about the risks of CV events, discuss the benefits and risks with your GP or rheumatologist. Note: This may not be a comprehensive list — ask your pharmacist or doctor for more information. Arthritis Australia advocates to government, business, industry and community leaders to improve care, management, support and quality of life for people with arthritis.

How do they work? What benefit can you expect from your treatment? When should they be taken? Tablets and capsules should be taken with food to reduce possible side effects. What is the dosage? NSAIDs come in different strengths. Treatment usually starts with a low dose. To minimise side effects, the lowest dose that controls symptoms is usually recommended.

To minimise side effects, sometimes a medicine to protect the stomach may be given see page 3. How long is the treatment continued? Are there any side effects? Most common possible side effects: The most common side effects are gastrointestinal and may include nausea feeling sick , vomiting, diarrhoea, constipation, heartburn and stomach pain or cramps. Other common side effects of NSAIDs include dizziness, lightheadedness, tiredness, headache, ringing in the ears tinnitis and increased blood pressure see Precautions.

NSAIDs can make heart failure or kidney failure worse. Fluid retention can lead to weight gain or swelling of ankles or legs. Kidney failure is more likely if you are also taking fluid tablets and certain blood pressure tablets see Precautions. Stomach or duodenal ulcers: If you develop severe stomach pains, pass blood or black stools, or vomit blood, stop taking the medicine immediately. You should see your doctor as soon as possible or go to the nearest emergency department. The risk of ulcers is higher if: you are older than 65 years you have had a previous stomach or duodenal ulcer you are also taking warfarin or other blood thinners, corticosteroid tablets or low-dose aspirin used by many people to help prevent a heart attack or stroke.

Your doctor may advise that you take an anti-ulcer medicine to help reduce the risk of getting a stomach or duodenal ulcer. Bleeding more easily than usual is often noticed. Allergy to NSAIDs can occur resulting in skin rashes or itchiness Shortness of breath may occur in some people with asthma see Precautions There are also a number of other uncommon side effects.

What precautions are necessary? Blood pressure Because NSAIDs can affect your blood pressure it is a good idea to have your blood pressure monitored monthly for the first two months. This is more important if you already have high blood pressure or you are on treatment for high blood pressure. Asthma Shortness of breath may occur in some people with asthma. Twice yearly checks are advised if you have no other risk factors.

Your kidney function may need to be monitored more frequently if you have other risk factors for reduced kidney function, such as being over 65 years old and taking blood pressure medicines or fluid tablets.

You should tell your doctor including your general practitioner, rheumatologist and other health professionals about all medicines you are taking, including herbal and naturopathic medicines. Despite the possible increased risk of ulcer, low doses of aspirin used to prevent heart attack and stroke can be used with NSAIDs.

Methotrexate for rheumatoid arthritis or other arthritis treatment can be taken safely with NSAIDs as long as your kidney function is normal. If you are taking anticoagulants such as warfarin or other blood thinners you should tell your doctor as combination with NSAIDs can increase the risk of bleeding. Heavy alcohol use more than 4 standard drinks in one session should be avoided while taking these medicines. Use in pregnancy and breastfeeding NSAIDs are not recommended during pregnancy unless specifically advised by your doctor.

If you are planning a family or you become pregnant you should discuss this with your doctor as soon as possible. Some studies suggest that if NSAIDs are taken around the time of conception there may be an increased risk of miscarriage. Paracetamol does not have these effects. NSAIDs can be excreted into breast milk but most are safe while breastfeeding. Keep all medicines out of reach of children. Important things to remember While taking NSAID you should see your doctor regularly to make sure the treatment is working and to minimise any possible side effects.

If you develop severe stomach pains, pass blood or black stools, or vomit blood, stop taking the medicine immediately. The information in this sheet has been obtained from various sources and has been reviewed by the Australian Rheumatology Association. Do not take more than one medicine containing an NSAID at the same time, unless your doctor recommends it.

If you are taking any over-the-counter NSAIDs, tell your doctor or pharmacist, particularly if you are due to undergo surgery or are starting a new medicine.

This page has been produced in consultation with and approved by:. Ankylosing spondylitis AS is a type of inflammatory arthritis that targets the joints of the spine. Antioxidants scavenge free radicals from the body's cells, and prevent or reduce the damage caused by oxidation. Antipsychotic medications work by altering brain chemistry to help reduce psychotic symptoms like hallucinations, delusions and disordered thinking. One child in every 1, in Australia is diagnosed with juvenile arthritis.

It is one of the most common chronic conditions to affect children. No special diet or 'miracle food' can cure arthritis, but some conditions may be helped by avoiding or including certain foods. Content on this website is provided for information purposes only. Information about a therapy, service, product or treatment does not in any way endorse or support such therapy, service, product or treatment and is not intended to replace advice from your doctor or other registered health professional.

The information and materials contained on this website are not intended to constitute a comprehensive guide concerning all aspects of the therapy, product or treatment described on the website. All users are urged to always seek advice from a registered health care professional for diagnosis and answers to their medical questions and to ascertain whether the particular therapy, service, product or treatment described on the website is suitable in their circumstances.

The State of Victoria and the Department of Health shall not bear any liability for reliance by any user on the materials contained on this website. Skip to main content. Home Medications. Decrease the text size Increase the text size Print this page Share. Home » Safety information » Alerts » All alerts. Safety advisory - inconsistent information about the known risk of miscarriage.

NSAIDs include the following medications: aspirin celecoxib diclofenac etoricoxib flurbiprofen ibuprofen indometacin previously known as indomethacin ketoprofen ketorolac trometamol mefenamic acid meloxicam naproxen parecoxib piroxicam sulindac.

Do not use at all during the last 3 months of pregnancy. Information for consumers Use of non-aspirin NSAIDs is known to be associated with an increase in the risk of miscarriage, particularly when taken close to the time of conception.

If you use any over-the-counter medicine, always read the label and follow the instructions. If you have any questions or concerns about this issue, talk to your health professional. Information for health professionals Health professionals are reminded of the increased risk of miscarriage associated with treatment with non-aspirin NSAIDs, particularly if taken close to the time of conception.

Reporting problems Consumers and health professionals are encouraged to report problems with medicines or vaccines. Please check and try again Agree to Terms required. Thank you for sharing our content. A message has been sent to your recipient's email address with a link to the content webpage. Your name: is required Error: This is required. Your email: is required Error: This is required Error: Not a valid value. Send to: is required Error: This is required Error: Not a valid value.

What it is used for How to take it Visual appearance Do I need a prescription? Over 65? Pregnant or planning a pregnancy? How to take it The way to take this medicine is: Oral.

This medicine is taken by mouth. Store below 25 degrees Celsius Shelf lifetime is 2 Years. Always read the label. If symptoms persist see your healthcare professional.



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